Size of the engines does play a big role but the biggest role is how much money you do spend on the correct parts combination, machine work and design assembly talents of your engine guy. Even the best can't do it with budget parts and the worst can;'t do it at all. lol.
You won't do it with any 23 degree heads that I am aware of. It takes 15 degree or better heads and tons of professional head work on them. plus everything else. Most of the heads capable of the really high power numbers cost a bundle and the lifter bores in the block need to be bored in different locations, with also special camshft lobe positions.
Trust me, for the power per dollar you are better off with a BB. I can do it and have done it, and several other buildrs have as well, but it costs tons.
Using a turbo system is another way to go and that works really good, but that also costs. You can also use an old school 8/71.
Ed